Our new saliva-based RDT for malaria detection is based on Electrochemical Impedance Spectroscopy (EIS) detection mechanism. We are going to detect P.falciparum lactate dehydrogenase, which is a biomarker for the presence of Malaria parasite, level in saliva. With this technology, our device will be able to fully quantify the level of infection; thus, the patients will only need to take appropriate amount of drugs. .
This is a great advantage of our device, since most Malaria RDT on current market can only offer qualitative readout, so the patients will have to take a maximum dose of drug treatment. This will potential lead to antimalarial drug resistance issue. More importantly, our approach to detect malaria parasite is based on saliva, which is non-invasive and less contagious comparing to the use of blood from most current RDT approach. We believe that saliva sample collection will be more favored by patients than finger-prick blood collection, especially when the patients are children or babies.